DBCO-amine (GMP)

DBCO-amine (GMP) is a GMP grade DBCO-amine (HY-W000423) . DBCO-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-amine is used in the synthesis of antibody-drug conjugates (ADCs) [1].

Product Specifications

CAS Number

[1255942-06-3]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Biochemical Assay Reagents

Type

GMP Small Molecules

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dbco-amine-gmp.html

Purity

99.80

Solubility

10 mM in DMSO

Smiles

O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCN

Molecular Formula

C18H16N2O

Molecular Weight

276.33

Precautions

H315, H319, H335

References & Citations

[1]Ermira Pazolli, et al. Splicing modulator antibody-drug conjugates and methods of use. WO2019232449A1.

Shipping Conditions

Dry Ice

Storage Conditions

Seal, protect from light, under nitrogen and store bellow -15°C

Scientific Category

GMP Small Molecules

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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