(±) -2-Propyl-4-pentenoic acid
(±) -2-Propyl-4-pentenoic acid (4-en-VPA) is a major toxic metabolite of Valproic acid. (±) -2-Propyl-4-pentenoic acid exhibits neuroteratogenicity[1][2].
Product Specifications
CAS Number
[1575-72-0]
Product Name Alternative
4-en-VPA; 2-Allylpentanoic acid
UNSPSC
12352211
Hazard Statement
H290, H314
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/racemic-2-propyl-4-pentenoic-acid.html
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C=CCC(CCC)C(O)=O
Molecular Formula
C8H14O2
Molecular Weight
142.20
Precautions
H290, H314
References & Citations
[1]W Tang, et, al. A comparative investigation of 2-propyl-4-pentenoic acid (4-ene VPA) and its alpha-fluorinated analogue: phase II metabolism and pharmacokinetics. Drug Metab Dispos. 1997 Feb;25 (2) :219-27.|[2]Gofflot F, et, al. In vitro neuroteratogenicity of valproic acid and 4-en-VPA. Neurotoxicol Teratol. Jul-Aug 1995;17 (4) :425-35.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
030663 100 µL
STAT3 (Signal transducer and activator of transcription 3, Acute-phase response factor)
Sign In for Pricing
View Details 
302349-ML405 100 µL
CHMP3 (Charged Multivesicular body Protein 3, Chromatin-modifying Protein 3, Neuroendocrine Differentiation Factor, Vacuolar Protein Sorting-Associated Protein 24, hVps24, CHMP3, CGI149, NEDF, VPS24) (MaxLight 405) discontinued
Sign In for Pricing
View Details 