Butein (Standard)
Butein (Standard) is the analytical standard of Butein. This product is intended for research and analytical applications. Butein is a cAMP-specific PDE inhibitor with an IC50 of 10.4 μM for PDE4[1]. Butein is a specific protein tyrosine kinase inhibitor with IC50s of 16 and 65 μM for EGFR and p60c-src in HepG2 cells[2]. Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a[3]. Butein is a SIRT1 activator (STAC) .
Product Specifications
CAS Number
487-52-5
Product Name Alternative
2’,3,4,4’-tetrahydroxy Chalcone (Standard)
UNSPSC
12352005
Target
Apoptosis; Autophagy; EGFR; Phosphodiesterase (PDE) ; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Autophagy; JAK/STAT Signaling; Metabolic Enzyme/Protease; Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/butein-standard.html
Smiles
OC1=CC=C(C(/C=C/C2=CC(O)=C(O)C=C2)=O)C(O)=C1
Molecular Formula
C15H12O5
Molecular Weight
272.25
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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