CDCP1, Human (312a.a, HEK293, His)

CDCP1 protein may be involved in cell adhesion and extracellular matrix association. Phosphorylation of CDCP1 may regulate the balance between anchorage and migration, proliferation, and differentiation. CDCP1 Protein, Human (312a.a, HEK293, His) is the recombinant human-derived CDCP1 protein, expressed by HEK293 , with C-6*His labeled tag.

Product Specifications

Product Name Alternative

CDCP1 Protein, Human (312a.a, HEK293, His), Human, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/cdcp1-protein-human-hek-293-his.html

Smiles

FEIALPRESNITVLIKLGTPTLLAKPCYIVISKRHITMLSIKSGERIVFTFSCQSPENHFVIEIQKNIDCMSGPCPFGEVQLQPSTSLLPTLNRTFIWDVKAHKSIGLELQFSIPRLRQIGPGESCPDGVTHSISGRIDATVVRIGTFCSNGTVSRIKMQEGVKMALHLPWFHPRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANYPEGFPEDELMTWQFVVPAHLRASVSFLNFNLSNCERKEERVEYYIPGSTTNPEVFKLEDKQPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQHPQNES

Molecular Formula

64866 (Gene_ID) Q9H5V8-3 (F30-S341) (Accession)

Molecular Weight

Approximately 45-70 kDa, based on SDS-PAGE under reducing conditions.

References & Citations

[1]Qi X, et al. CDCP1: A promising diagnostic biomarker and therapeutic target for human cancer. Life Sci. 2022 Jul 15;301:120600.|[2]He Y, et al. CDCP1 enhances Wnt signaling in colorectal cancer promoting nuclear localization of β-catenin and E-cadherin. Oncogene. 2020 Jan;39 (1) :219-233.|[3]Kajiwara K, et al. CDCP1 promotes compensatory renal growth by integrating Src and Met signaling. Life Sci Alliance. 2021 Feb 11;4 (4) :e202000832.|[4]Conze T, et al. CDCP1 is a novel marker for hematopoietic stem cells. Ann N Y Acad Sci. 2003 May;996:222-6.|[5]Scherl-Mostageer M, et al. Identification of a novel gene, CDCP1, overexpressed in human colorectal cancer. Oncogene. 2001 Jul 19;20 (32) :4402-8.