P-Selectin, Rhesus Macaque (HEK293, Fc)

P-Selectin Protein, Rhesus Macaque (HEK293, His) is a member of the selectin family of cell adhesion molecules. P-selectin (CD62P) has an N-terminal lectin domain, an epidermal growth factor motif, (generally) nine regulatory protein repeats, a transmembrane section and a short intracytoplasmic tail. P-selectin mediates leukocyte rolling on stimulated endothelial cells and heterotypic aggregation of activated platelets onto leukocytes. P-selectin mediates heterotypic aggregation of activated platelets to cancer cells and adhesion of cancer cells to stimulated endothelial cells. P-selectin glycoprotein ligand-1 (PSGL-1) is a major ligand for P-selectin[1][2][3]. P-Selectin Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived P-Selectin protein, expressed by HEK293 , with C-hFc labeled tag.

WTYHYSTKAY SWNTSRKYCQ NRYTDLVAIQ NKKEIDYLNE VLPYYSTYYW IGIRKSNKTW TWVGTKKALT KEAENWADNE PNNKRNNEDC VEIYIKSPSA PGKWNDEHCL KKKHALCYTA SCQDMSCSKQ GECLETIGNY TCSCYPGFYG PECEYVTECG ELELPQHVLM NCSHPLGNFS FNSQCSFHCA DGYQVNGPSK LECLASGIWT HKPPQCLAAQ CPPLKIPERG NMTCLHSAKA FQHQSSCGFS CEEGFVLVGP EVVQCTASGV WTAPAPVCKA VQCQHLEAPS EGTMDCIHPL AAFAYGSNCK FECQLGYRVR GLDTLRCIGS GHWSAPLPTC EAISCEPLES PVHGSMDCSP SLRAFQYDTN CSFRCAEGFM LRGADIVRCD NLGQWTAPAP VCQALQCQDL PVPNEAQVNC SHPFGAFRYQ SVCSFTCNED LLLVGASVLQ CLATGNWNSV PPECQAIPCT PLLSPQNGTM TCVQPLGSSS YKSTCHFICD EGFSLSGPER LDCTRSGRWT DSPPTCEAIK CPELFAPEQG SLDCSDTHGE FNVGSTCHFS CNKGFKLEGP NNVKCTTSGR WSATPPACKG IASLPSPGVQ CPALTTPGQG TMHCRHHPGT FGFNTTCYFG CNAGFTLTGD SILSCRPSGQ WTAVTPTCRA VKCPELHVNK PIVMNCSNLW GNFSYGSICS FHCLEGQLLN GSAQTACQEN GHWSTTVPTC QAGPLTIQEA