Xantphos

Xantphos (9,9-Dimethyl-4,5-bis (diphenylphosphino) xanthene) is a bisphosphine ligand. Xantphos coordinates to metals in either cis or trans chelation mode. Xantphos acts as a key ligand in palladium or platinum catalyzed reactions. Xantphos can be used in the construction of heterocyclic compounds in organic synthesis[1][2][3].

Product Specifications

CAS Number

[161265-03-8]

Product Name Alternative

9,9-Dimethyl-4,5-bis (diphenylphosphino) xanthene

UNSPSC

12352200

Hazard Statement

H315, H319, H335

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/xantphos.html

Purity

99.93

Solubility

DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : 1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC1(C)C2=C(C(P(C3=CC=CC=C3)C4=CC=CC=C4)=CC=C2)OC5=C1C=CC=C5P(C6=CC=CC=C6)C7=CC=CC=C7

Molecular Formula

C39H32OP2

Molecular Weight

578.62

Precautions

H315, H319, H335

References & Citations

[1]Manley PJ, et al. A new synthesis of naphthyridinones and quinolinones: palladium-catalyzed amidation of o-carbonyl-substituted aryl halides. Org Lett. 2004 Jul 8;6 (14) :2433-5.|[2]Petöcz G, et al. Xantphos as cis-and trans-chelating ligand in square-planar platinum (II) complexes. Hydroformylation of styrene with platinum–xantphos–tin (II) chloride system. Journal of organometallic chemistry, 2004, 689 (7) : 1188-1193. |[3]Gao GY, et al. General synthesis of meso-amidoporphyrins via palladium-catalyzed amidation. Org Lett. 2004 May 27;6 (11) :1837-40.