Sulbactam

Sulbactam (CP45899) is a competitive, irreversible beta-lactamase inhibitor. Sulbactam shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex[1][2].

Product Specifications

CAS Number

[68373-14-8]

Product Name Alternative

CP45899

UNSPSC

12352005

Hazard Statement

H302

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Sulbactam.html

Concentration

10mM

Purity

99.75

Solubility

DMSO : ≥ 100 mg/mL|H2O : 20 mg/mL (ultrasonic)

Smiles

O=C([C@@H](C(C)(C)S([C@]1([H])C2)(=O)=O)N1C2=O)O

Molecular Formula

C8H11NO5S

Molecular Weight

233.25

Precautions

H302

References & Citations

[1]Noguchi JK, et al. Sulbactam: a beta-lactamase inhibitor. Clin Pharm. 1988;7 (1) :37-51.|[2]Lin HS, et al. Sulbactam treatment for pneumonia involving multidrug-resistant Acinetobacter calcoaceticus-Acinetobacter baumannii complex. Infect Dis (Lond) . 2015;47 (6) :370-378.|[3]Betrosian AP, et al. Ampicillin-sulbactam: an update on the use of parenteral and oral forms in bacterial infections. Expert Opin Drug Metab Toxicol. 2009;5 (9) :1099-1112.