K114
K114, a fluorescent Congo Red analogue, binds tightly to amyloid fibrils with an EC50 of 20-30 nM[1]. K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI) [2].
Product Specifications
CAS Number
872201-12-2
UNSPSC
12171500
Hazard Statement
H319-H413
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/k114.html
Purity
99.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
BrC1=CC(/C=C/C2=CC=C(O)C=C2)=CC=C1/C=C/C3=CC=C(O)C=C3
Molecular Formula
C22H17BrO2
Molecular Weight
393.27
Precautions
P264-P273-P280-P305+P351+P338-P501
References & Citations
[1]LeVine H 3rd, et al. Mechanism of A beta (1-40) fibril-induced fluorescence of (trans, trans) -1-bromo-2,5-bis (4-hydroxystyryl) benzene (K114) . Biochemistry. 2005 Dec 6;44 (48) :15937-43.|[2]Selmani V, et al. K114 (trans, trans) -bromo-2,5-bis (4-hydroxystyryl) benzene is an efficient detector of cationic amyloid fibrils. Protein Sci. 2015 Mar;24 (3) :420-5.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
DEA15585 250 mg
Diethyl 2- (((2-methyl-4-quinolyl) amino) methylene) propane-1,3-dioate
Sign In for Pricing
View Details 