TRC-766
TRC-766 is a negative control of RTC-5 (TRC-382) . TRC-766 binds protein phosphatase 2A (PP2A) and does not activate the phosphatase[1].
Product Specifications
CAS Number
[1810734-44-1]
Product Name Alternative
DBK-766
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/trc-766.html
Purity
98.07
Solubility
DMSO : 150 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=C(OC(F)(F)F)C=C1)(N(CCCN2C3=CC(Cl)=CC=C3CCC4=CC=CC=C42)C)=O
Molecular Formula
C25H24ClF3N2O3S
Molecular Weight
524.98
References & Citations
[1]Kimberly McClinch, et al. Small-Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer. Cancer Res. 2018 Apr 15;78 (8) :2065-2080.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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