UKI-1
UKI-1 (WX-UK1) is a potent urokinase-type plasminogen activator (uPA) inhibitor with a Ki of 0.41 μM. UKI-1 is also a low molecular weight serine protease inhibitor. UKI-1 is a potent antimetastatic agent and inhibits the invasive capacity of carcinoma cells[1][2].
Product Specifications
CAS Number
[220355-63-5]
Product Name Alternative
WX-UK1; UKI-1C
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PAI-1; Ser/Thr Protease
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/UKI-1.html
Purity
96.13
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1CCN(C([C@@H](NS(=O)(C2=C(C(C)C)C=C(C(C)C)C=C2C(C)C)=O)CC3=CC=CC(C(N)=N)=C3)=O)CC1)OCC
Molecular Formula
C32H47N5O5S
Molecular Weight
613.81
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-100415/UKI-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-100415/UKI-1-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
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