Carmoterol (hydrochloride)

Carmoterol hydrochloride is a highly potent, selective and long-acting β2-adrenoceptor agonist with the pEC50 of 10.19. Carmoterol has 53 times higher affinity for the β2-adrenoceptors than for the β1-adrenoceptors. Carmoterol hydrochloride can be used for the research of asthma and chronic obstructive pulmonary disease (COPD) [1][2].

Product Specifications

CAS Number

[137888-11-0]

UNSPSC

12352005

Hazard Statement

H301

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/carmoterol-hydrochloride.html

Purity

98.73

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1NC2=C(C([C@@H](O)CN[C@H](C)CC3=CC=C(OC)C=C3)=CC=C2O)C=C1.Cl

Molecular Formula

C21H25ClN2O4

Molecular Weight

404.89

Precautions

H301

References & Citations

[1]Mario Cazzola, et al. β (2) -adrenoceptor agonists: current and future direction. Br J Pharmacol. 2011 May;163 (1) :4-17.|[2]Giuseppe Rossoni, et al. Positive interaction of the novel beta2-agonist carmoterol and tiotropium bromide in the control of airway changes induced by different challenges in guinea-pigs. Pulm Pharmacol Ther. 2007;20 (3) :250-7.