Palicourein
Palicourein is a 37 amino acid cyclic polypeptide. Palicourein inhibits the in vitro cytopathic effects of HIV-1RF infection of CEM-SS cells with an EC50 value of 0.1 μM and an IC50 value of 1.5 μM[1].
Product Specifications
CAS Number
331714-57-9
UNSPSC
12352209
Target
Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/palicourein.html
Solubility
10 mM in DMSO
Smiles
O=C(CN)N[C@H](C(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NC3)=O)CC(C)C)=O)C)=O)C)=O)CO)=O)CC4=CC=C(O)C=C4)=O)[C@@H](C)O)=O)CSSC[C@H](NC5=O)C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CC(N)=O)=O)CCCNC(N)=N)=O)CCCCN)=O)=O)C(C)C)=O)CCC2)=O)[C@H](CC)C)=O)C(C)C)=O)CCCNC(N)=N)=O)CSSC[C@H](NC6=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H]5CC(C)C)=O)=O)CC(O)=O)=O)CO)=O)CCCNC(N)=N)=O)CC(O)=O)=O)CC(O)=O)=O)=O)[C@@H](C)O)=O)CCC(O)=O)=O)=O)CSSC[C@H](NC3=O)C(N[C@H]6[C@@H](C)O)=O)=O)CC7=CC=CC=C7)=O)[C@@H](C)O)=O)CCC1)=O)CC(O)=O
Molecular Formula
C159H250N48O56S6
Molecular Weight
3922.36
References & Citations
[1]Bokesch HR, et al. A novel anti-HIV macrocyclic peptide from Palicourea condensata. J Nat Prod. 2001 Feb;64 (2) :249-50.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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