Imperatorin (Standard)

Imperatorin (Standard) is the analytical standard of Imperatorin. This product is intended for research and analytical applications. Imperatorin is an effective of NO synthesis inhibitor (IC50=9.2 μmol), which also is a BChE inhibitor (IC50=31.4 μmol) . Imperatorin is a weak agonist of TRPV1 with EC50 of 12.6±3.2 μM.

Product Specifications

CAS Number

[482-44-0]

Product Name Alternative

Ammidin (Standard)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Cholinesterase (ChE) ; Reference Standards; TRP Channel

Type

Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/imperatorin-standard.html

Purity

98.77

Smiles

O=C1C=CC2=CC3=C(OC=C3)C(OC/C=C(C)/C)=C2O1

Molecular Formula

C16H14O4

Molecular Weight

270.28

Precautions

H302, H315, H319, H335

References & Citations

[1]Kozio? E, et al. Imperatorin-pharmacological meaning and analytical clues: profound investigation. Phytochem Rev. 2016;15:627-649.|[2]Chen X, et al. Furanocoumarins are a novel class of modulators for the transient receptor potential vanilloid type 1 (TRPV1) channel. J Biol Chem. 2014 Apr 4;289 (14) :9600-10.|[3]Budzynska B, et al. Effects of imperatorin on scopolamine-induced cognitive impairment and oxidative stress in mice. Psychopharmacology (Berl) . 2015 Mar;232 (5) :931-42.