Rilmenidine-d4
Rilmenidine-d4 is the deuterium labeled Rilmenidine. Rilmenidine, an innovative antihypertensive agent, is an orally active, selective I1 imidazoline receptor agonist. Rilmenidine is an alpha 2-adrenoceptor agonist. Rilmenidine induces autophagy. Rilmenidine acts both centrally by reducing sympathetic overactivity and in the kidney by inhibiting the Na+/H+ antiport. Rilmenidine modulates proliferation and stimulates the proapoptotic protein Bax thus inducing the perturbation of the mitochondrial pathway and apoptosis in human leukemic K562 cells[1][2][3].
Product Specifications
CAS Number
85047-14-9
UNSPSC
12352005
Target
Adrenergic Receptor; Apoptosis; Autophagy; Imidazoline Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Autophagy; GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Cancer; Cardiovascular Disease
Solubility
10 mM in DMSO
Smiles
[2H]C1([2H])C([2H])(OC(NC(C2CC2)C3CC3)=N1)[2H]
Molecular Formula
C10H12D4N2O
Molecular Weight
184.27
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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