(Rac) -Arnebin 1

(Rac) -Arnebin 1 ((Rac) -β, β-Dimethylacrylalkannin) is the racemate of β, β-Dimethylacrylalkannin and/or β, β-Dimethylacrylshikonin. β, β-Dimethylacrylalkannin and β, β-Dimethylacrylshikonin are napthoquinones isolated from Arnebia nobilis. β, β-Dimethylacrylshikonin has anti-tumor activity[1].

Product Specifications

CAS Number

[5162-01-6]

Product Name Alternative

(Rac) -β, β-Dimethylacrylalkannin; (Rac) -β, β-Dimethylacrylshikonin

UNSPSC

12352005

Target

HIF/HIF Prolyl-Hydroxylase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others; Cancer

Assay Protocol

https://www.medchemexpress.com/rac-arnebin-1.html

Concentration

10mM

Purity

99.88

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

C/C(C)=C\C(OC(C(C1=O)=CC(C2=C1C(O)=CC=C2O)=O)C/C=C(C)\C)=O

Molecular Formula

C21H22O6

Molecular Weight

370.40

References & Citations

[1]Zeng Z, et al. Arnebin-1 promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway. Int J Mol Med. 2015 Sep;36 (3) :685-97.