5-Hydroxyindole-3-acetic acid-13C6

5-Hydroxyindole-3-acetic acid-13C6 is the 13C-labeled 5-Hydroxyindole-3-acetic acid. 5-Hydroxyindole-3-acetic acid is the main metabolite of serotonin or metanephrines, which can be used as a biomarker of neuroendocrine tumors.

Product Specifications

CAS Number

[2733322-34-2]

UNSPSC

12352005

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/5-hydroxyindole-3-acetic-acid-13c6.html

Solubility

10 mM in DMSO

Smiles

O=C(CC1=CN[13C]2=[13C]1[13CH]=[13C]([13CH]=[13CH]2)O)O

Molecular Formula

C4 13C6H9NO3

Molecular Weight

197.14

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Corcuff JB, et al. Urinary sampling for 5HIAA and metanephrines determination: revisiting the recommendations. Endocr Connect. 2017 Aug;6 (6) :R87-R98.