IBS008738
IBS008738 is a potent TAZ activator. IBS008738 stabilizes TAZ, increases the unphosphorylated TAZ level, enhances the association of MyoD with the myogenin promoter, upregulates MyoD-dependent gene transcription, and competes with myostatin in C2C12 cells. IBS008738 enhances myogenesis in C2C12 cells and facilitates muscle repair in a muscle injury model[1][2].
Product Specifications
CAS Number
[385425-03-6]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
YAP
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ibs008738.html
Purity
98.22
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=C(/N=C/N2CCOCC2)N=CN1C3=CC=C(C)C=C3)C4=CC=CC=C4
Molecular Formula
C22H22N4O2
Molecular Weight
374.44
Precautions
H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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