Poloxamer 188 (Highly Pure Surfactant)

<strong>Poloxamer 188 (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2010444_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 mL_x000D_ <strong>Molecular Weight or Concentration:</strong> 0.1_x000D_ <strong>Supplied as:</strong> 10% Solution_x000D_ <strong>Appearance:</strong> Solution_x000D_ <strong>Applications:</strong> highly pure nonionic copolymer surfactant with applications in flow cytometry._x000D_ <strong>Storage:</strong> RT_x000D_ <strong>Keywords:</strong> Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)_x000D_ <strong>Grade:</strong> Biotechnology grade. All solid components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Wang T, Markham A, Thomas SJ, Wang N, Huang L, Clemens M, Rajagopalan N._x000D_ Solution Stability of Poloxamer 188 Under Stress Conditions. J Pharm Sci. 2019_x000D_ Mar;108(3):1264-1271._x000D_ _x000D_ 2: Gibbs WJ, Hagemann TM. Purified poloxamer 188 for sickle cell vaso-occlusive_x000D_ crisis. Ann Pharmacother. 2004 Feb;38(2):320-4._x000D_ _x000D_ 3: Grapentin C, Müller C, Kishore RSK, Adler M, ElBialy I, Friess W, Huwyler J,_x000D_ Khan TA. Protein-Polydimethylsiloxane Particles in Liquid Vial Monoclonal_x000D_ Antibody Formulations Containing Poloxamer 188. J Pharm Sci. 2020_x000D_ Aug;109(8):2393-2404._x000D_ _x000D_ 4: Dong H, Qin Y, Huang Y, Ji D, Wu F. Poloxamer_188 rescues MPTP-induced_x000D_ lysosomal membrane integrity impairment in cellular and mouse models of_x000D_ Parkinson's disease. Neurochem Int. 2019 Jun;126:178-186._x000D_ _x000D_ 5: Moloughney JG, Weisleder N. Poloxamer_188 (p188) as a membrane resealing_x000D_ reagent in biomedical applications. Recent Pat Biotechnol. 2012 Dec;6(3):200-11._x000D_ _x000D_ 6: Mehdipour M, Daghigh Kia H, Martínez-Pastor F. Poloxamer_188 exerts a_x000D_ cryoprotective effect on rooster sperm and allows decreasing glycerol_x000D_ concentration in the freezing extender. Poult Sci. 2020 Nov;99(11):6212-6220._x000D_ _x000D_ 7: Guler N, Abro S, Emanuele M, Iqbal O, Hoppensteadt D, Fareed J. The_x000D_ Protective Effect of Poloxamer_188 on Platelet Functions. Clin Appl Thromb_x000D_ Hemost. 2017 Nov;23(8):987-991._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/32109347/">8: Czeiszperger TL, Wang MP, Chung CS. Membrane stabilizer Poloxamer 188_x000D_ improves yield of primary isolated rat cardiomyocytes without impairing_x000D_ function. Physiol Rep. 2020 Feb;8(4):e14382. </a>_x000D_ _x000D_ <strong>Products Related to Poloxamer 188 (Highly Pure) and other surfactants used in Cellular Biology</strong><a href="https://moleculardepot.com/product-category/Chemicals/">: Chemicals</a>