N, N'-Carbonyldiimidazole

N, N'-Carbonyldiimidazole (1,1'-Carbonyldiimidazole) is a highly reactive carboxylating reagent that can activate hydroxyl groups to form reactive carbonyl groups. N, N'-Carbonyldiimidazole can be used as a coupling agent and a peptide synthesis reagent[1][2][3].

Product Specifications

CAS Number

[530-62-1]

Product Name Alternative

1,1'-Carbonyldiimidazole

UNSPSC

12352005

Hazard Statement

H302, H314, H360

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/n-n-carbonyldiimidazole.html

Purity

99.83

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(N1C=NC=C1)N2C=NC=C2

Molecular Formula

C7H6N4O

Molecular Weight

162.15

Precautions

H302, H314, H360

References & Citations

[1]Ho J, et al. N, N'-Carbonyldiimidazole-mediated functionalization of superparamagnetic nanoparticles as vaccine carrier. Colloids Surf B Biointerfaces. 2011 Mar;83 (1) :83-90.|[2]Huang Q, et al. Preparation and cyclodextrin solubilization of the antibacterial agent benzoyl metronidazole. ScientificWorldJournal. 2013 Jul 21;2013:306476. |[3]Paul R, et al. N, N'-Carbonyldiimidazole, a New Peptide Forming Reagent1. Journal of the American Chemical Society, 1960, 82 (17) : 4596-4600.