MRTF/SRF-IN-1
MRTF/SRF-IN-1 (example 41) is an inhibitor of both myocardin-related transcription factor and serum response factor (MRTF/SRF) . MRTF/SRF-IN-1 can be used for research for preventing cancer and fibrosis[1].
Product Specifications
CAS Number
1922098-90-5
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mrtf-srf-in-1.html
Purity
99.68
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1CC(CC(F)(C1)F)C(NC2=CC=C(C=C2)Cl)=O)C3=CC(F)=CC(C4=CC=NC=C4)=C3
Molecular Formula
C24H19ClF3N3O2
Molecular Weight
473.87
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
[1]Larsen Scott D, et al. Preparation of substituted piperidine-3-carboxamides as inhibitors of myocardin-related transcription factor and serum response factor (MTRF/SRF) -mediated gene transcription. World Intellectual Property Organization, WO2016073847 A2. 2016-05-12.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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