MRTF/SRF-IN-1

MRTF/SRF-IN-1 (example 41) is an inhibitor of both myocardin-related transcription factor and serum response factor (MRTF/SRF) . MRTF/SRF-IN-1 can be used for research for preventing cancer and fibrosis[1].

Product Specifications

CAS Number

[1922098-90-5]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Ras

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mrtf-srf-in-1.html

Purity

99.68

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N1CC(CC(F)(C1)F)C(NC2=CC=C(C=C2)Cl)=O)C3=CC(F)=CC(C4=CC=NC=C4)=C3

Molecular Formula

C24H19ClF3N3O2

Molecular Weight

473.87

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

References & Citations

[1]Larsen Scott D, et al. Preparation of substituted piperidine-3-carboxamides as inhibitors of myocardin-related transcription factor and serum response factor (MTRF/SRF) -mediated gene transcription. World Intellectual Property Organization, WO2016073847 A2. 2016-05-12.