11-Dehydrocorticosterone
Product Specifications
Product Name Alternative
SHP-141
UNSPSC Description
11-Dehydrocorticosterone is a endogenous corticosteroid. 11-Dehydrocorticosterone can be a source of transcriptionally active glucocorticoid in cardiac myocytes and fibroblasts. 11-Dehydrocorticosterone can increase SGK mRNA expression in cardiac fibroblast[1].
Target Antigen
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/11-dehydrocorticosterone.html
Purity
95.24
Solubility
DMSO : 30 mg/mL (ultrasonic)
Smiles
C[C@@]1(C2)[C@@H](C(CO)=O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])C2=O)=O
Molecular Weight
344.44
References & Citations
[1]Sheppard KE, et al. 11Beta-hydroxysteroid dehydrogenase 1 transforms 11-dehydrocorticosterone into transcriptionally active glucocorticoid in neonatal rat heart. Endocrinology. 2002;143(1):198-204.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-113447/11-Dehydrocorticosterone-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-113447/11-Dehydrocorticosterone-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
72-23-1
Available Sizes
Curated Selection
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