Lapisteride
Lapisteride (CS 891) is an orally active 5α-reductase inhibitor. Lapisteride can inhibit 5α-reductaseactivity in the hair follicles (HF) . Lapisteride can be used in prostatic hyperplasia and androgenic alopecia research[1][2].
Product Specifications
CAS Number
142139-60-4
Product Name Alternative
CS 891
UNSPSC
12352005
Target
5 alpha Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/lapisteride.html
Purity
99.0
Solubility
Ethanol : 100 mg/mL (ultrasonic)
Smiles
C[C@@]12[C@](CC[C@@H]2C(NC(C)(C3=CC=C(C=C3)OC)C)=O)([H])[C@@]4([H])[C@@](CC1)([H])[C@@]5([C@@](NC(C=C5)=O)([H])CC4)C
Molecular Formula
C29H40N2O3
Molecular Weight
464.64
References & Citations
[1]Yada S, et al. Solid phase transition of CS-891 enantiotropes during grinding. Int J Pharm. 2003 Apr 14;255 (1-2) :69-79. |[2]Niiyama S, et al. The novel drug CS-891 inhibits 5alpha-reductase activity in freshly isolated dermal papilla of human hair follicles. Eur J Dermatol. 2000 Dec;10 (8) :593-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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