Direct Violet 1

Direct Violet 1, an azo dye, is a textile dye. Direct Violet 1 is also the protein-protein interaction (PPI) between the SARS-CoV-2 spike protein and ACE2 inhibitor with IC50s of 1.47-2.63 μM[1][2].

Product Specifications

CAS Number

[2586-60-9]

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

SARS-CoV

Type

Dye Reagents

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/direct-violet-1.html

Solubility

H2O : 62.5 mg/mL (ultrasonic)

Smiles

O=S(C1=CC(O)=C2C(/N=N/C3=CC=C(C4=CC=C(/N=N/C5=C(N)C=CC6=CC(S(=O)(O[Na])=O)=CC(O)=C56)C=C4)C=C3)=C(N)C=CC2=C1)(O[Na])=O

Molecular Formula

C32H22N6Na2O8S2

Molecular Weight

728.66

Precautions

H302, H315, H319, H335

References & Citations

[1]Damir Bojadzic, et al. Small-Molecule In Vitro Inhibitors of the Coronavirus Spike-ACE2 Protein-Protein Interaction as Blockers of Viral Attachment and Entry for SARS-CoV-2. bioRxiv, 2020 Oct 22.|[2]Wafaa M Abd El-Rahim, et al. Genotoxicity studies on the removal of a direct textile dye by a fungal strain, in vivo, using micronucleus and RAPD-PCR techniques on male rats. J Appl Toxicol. 2008 May;28 (4) :484-90.