Direct Violet 1
Direct Violet 1, an azo dye, is a textile dye. Direct Violet 1 is also the protein-protein interaction (PPI) between the SARS-CoV-2 spike protein and ACE2 inhibitor with IC50s of 1.47-2.63 μM[1][2].
Product Specifications
CAS Number
2586-60-9
UNSPSC
12171500
Hazard Statement
H302, H315, H319, H335
Target
SARS-CoV
Type
Dye Reagents
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/direct-violet-1.html
Solubility
H2O : 62.5 mg/mL (ultrasonic)
Smiles
O=S(C1=CC(O)=C2C(/N=N/C3=CC=C(C4=CC=C(/N=N/C5=C(N)C=CC6=CC(S(=O)(O[Na])=O)=CC(O)=C56)C=C4)C=C3)=C(N)C=CC2=C1)(O[Na])=O
Molecular Formula
C32H22N6Na2O8S2
Molecular Weight
728.66
Precautions
H302, H315, H319, H335
References & Citations
[1]Damir Bojadzic, et al. Small-Molecule In Vitro Inhibitors of the Coronavirus Spike-ACE2 Protein-Protein Interaction as Blockers of Viral Attachment and Entry for SARS-CoV-2. bioRxiv, 2020 Oct 22.|[2]Wafaa M Abd El-Rahim, et al. Genotoxicity studies on the removal of a direct textile dye by a fungal strain, in vivo, using micronucleus and RAPD-PCR techniques on male rats. J Appl Toxicol. 2008 May;28 (4) :484-90.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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