A12-Iso5-2DC18
Product Specifications
UNSPSC Description
A12-Iso5-2DC18, an ionizable cationic lipid, is a potent mRNA delivery lipid vehicle[1].
Target Antigen
Liposome
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/a12-iso5-2dc18.html
Solubility
10 mM in DMSO
Smiles
CCCCCCCC/C=C\CCCCCCCC1(CCCCCCC/C=C\CCCCCCCC)C=NC(N1CCCN(C)C)C(OCC)=O
Molecular Weight
700.18
References & Citations
[1]Miao L, et al. Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation. Nat Biotechnol. 2019 Oct;37(10):1174-1185.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151511/A12-Iso5-2DC18-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151511/A12-Iso5-2DC18-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2412492-06-7
Available Sizes
Curated Selection
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