SB-258585
SB-258585 is a selective ligand with high affinity for the 5-HT6 receptor, with a pKi value of 8.53[1].
Product Specifications
CAS Number
209480-63-7
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sb-258585.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(I)C=C1)(NC2=CC=C(OC)C(N3CCN(C)CC3)=C2)=O
Molecular Formula
C18H22IN3O3S
Molecular Weight
487.36
References & Citations
[1]Hirst WD, et al. Characterization of [ (125) I]-SB-258585 binding to human recombinant and native 5-HT (6) receptors in rat, pig and human brain tissue. Br J Pharmacol. 2000;130 (7) :1597-1605.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT6 Receptor
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