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SB-258585

SB-258585 is a selective ligand with high affinity for the 5-HT6 receptor, with a pKi value of 8.53[1].

Product Specifications

CAS Number

209480-63-7

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sb-258585.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=CC=C(I)C=C1)(NC2=CC=C(OC)C(N3CCN(C)CC3)=C2)=O

Molecular Formula

C18H22IN3O3S

Molecular Weight

487.36

References & Citations

[1]Hirst WD, et al. Characterization of [ (125) I]-SB-258585 binding to human recombinant and native 5-HT (6) receptors in rat, pig and human brain tissue. Br J Pharmacol. 2000;130 (7) :1597-1605.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT6 Receptor

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