Human Sphingosine Kinase 1

<strong>Human Sphingosine Kinase 1</strong>_x000D_ <strong>Catalog number:</strong> B2016634_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 47 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −80°C_x000D_ <strong>Keywords:</strong> SPHK 1_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong> _x000D_ 1: Bonica J, Mao C, Obeid LM, Hannun YA. Transcriptional Regulation of Sphingosine Kinase 1 Cells. 2020 Nov 8;9(11):2437. _x000D_ 2: Rohrbach T, Maceyka M, Spiegel S. Sphingosine kinase and sphingosine-1-phosphate in liver pathobiology Crit Rev Biochem Mol Biol. 2017 Oct;52(5):543-553. _x000D_ 3: Geffken K, Spiegel S. Sphingosine kinase 1 in breast cancer Adv Biol Regul. 2018 Jan;67:59-65. _x000D_ 4: Tsuchida J, Nagahashi M, Nakajima M, Katsuta E, Rashid OM, Qi Q, Yan L, Okuda S, Takabe K, Wakai T. Sphingosine Kinase 1 is Associated With Immune Cell-Related Gene Expressions in Human Breast Cancer J Surg Res. 2020 Dec;256:645-656. _x000D_ 5: Bao Y, Guo Y, Zhang C, Fan F, Yang W. Sphingosine Kinase 1 and Sphingosine-1-Phosphate Signaling in Colorectal Cancer Int J Mol Sci. 2017 Oct 8;18(10):2109. _x000D_ 6: Truman JP, Ruiz CF, Trayssac M, Mao C, Hannun YA, Obeid LM. Sphingosine kinase 1 downregulation is required for adaptation to serine deprivation FASEB J. 2021 Feb;35(2):e21284. _x000D_ 7: Zheng X, Li W, Ren L, Liu J, Pang X, Chen X, Kang D, Wang J, Du G. The sphingosine kinase-1/sphingosine-1-phosphate axis in cancer: Potential target for anticancer therapy Pharmacol Ther. 2019 Mar;195:85-99. _x000D_ 8: Pyne NJ, Pyne S. Sphingosine Kinase 1: A Potential Therapeutic Target in Pulmonary Arterial Hypertension? Trends Mol Med. 2017 Sep;23(9):786-798. _x000D_ 9: Carr JM, Mahalingam S, Bonder CS, Pitson SM. Sphingosine kinase 1 in viral infections Rev Med Virol. 2013 Mar;23(2):73-84. _x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/33123153">10: Wang X, Yang Y, Cai WQ, Lu Y. The Relationship of Sphingosine Kinase 1 With Pyroptosis Provides a New Strategy for Tumor Therapy Front Immunol. 2020 Oct 2;11:574990. </a>_x000D_ <br><strong>Products Related to Human Sphingosine Kinase 1 can be found at</strong> <a href="https://moleculardepot.com/product-category/Enzymes/"> Enzymes</a>