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Asymmetric dimethylarginine-d7 (hydrochloride hydrate)

Asymmetric dimethylarginine-d7 (hydrochloride hydrate) is the deuterium labeled Asymmetric dimethylarginine. Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS), and functions as a marker of endothelial dysfunction in a num

Product Specifications

Product Name Alternative

NG, NG-Dimethylarginine-d7 (hydrochloride hydrate)

UNSPSC

12352211

Target

Endogenous Metabolite; Isotope-Labeled Compounds; NO Synthase

Type

Isotope-Labeled Compounds

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; Others

Applications

Cancer-programmed cell death

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/asymmetric-dimethylarginine-d7-hydrochloride-hydrate.html

Solubility

10 mM in DMSO

Smiles

CN(C)C(NC([2H])([2H])C([2H])([2H])C([2H])([2H])C(N)([2H])C(O)=O)=N.Cl.[xH2O]

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Hudson CL, et al. The cardiovascular risk marker asymmetric dimethylarginine is elevated in asymptomatic, untreated HIV-1 infection and correlates with markers of immune activation and disease progression. Ann Clin Biochem. 2014 Sep;51 (Pt 5) :568-75.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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