LpxC-IN-15
LpxC-IN-15 ((S) -13j) is a potent LpxC inhibitor with Ki values of 9.05, 5.6 nM for EcLpxC C63A, PaLpxC, respectively. LpxC-IN-15 shows antibacterial activity[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/lpxc-in-15.html
Smiles
O=C(NO)[C@@H](OCC1=CC=C(C=C1)C#CC2=CC=C(C=C2)CN3CCOCC3)CNC(C4=CC(C=CN5)=C5C=C4)=O
Molecular Formula
C32H32N4O5
Molecular Weight
552.62
References & Citations
[1]Mielniczuk S, et al. Development of Fragment-Based Inhibitors of the Bacterial Deacetylase LpxC with Low Nanomolar Activity. J Med Chem. 2024 Oct 10;67 (19) :17363-17391.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7257374-01 48 Well
Guinea Pig A Disintegrin And Metalloprotease 33, ADAM33 ELISA Kit
Ask
View Details MBS7257374-02 96 Well
Guinea Pig A Disintegrin And Metalloprotease 33, ADAM33 ELISA Kit
Ask
View Details MBS7257374-03 5x 96 Well
Guinea Pig A Disintegrin And Metalloprotease 33, ADAM33 ELISA Kit
Ask
View Details 
MBS7257374-04 10x 96 Well
Guinea Pig A Disintegrin And Metalloprotease 33, ADAM33 ELISA Kit
Ask
View Details 
036145-AP 200 µL
GNL2, NT (GNL2, NGP1, Nucleolar GTP-binding protein 2, Autoantigen NGP-1) (AP) discontinued
Ask
View Details