11-Dehydro-thromboxane B2-13C5

11-Dehydro-thromboxane B2-13C5 is 13C labeled 11-Dehydro-thromboxane B2 (HY-113420) . 11-Dehydro-thromboxane B2 is a platelet hemagglutinin. Thromboxane inhibition was assessed by urinary excretion levels of 11-Dehydro-thromboxane B2. 11-Dehydro-thromboxane B2 can be used in the study of atherosclerotic thrombosis[1][2].

Product Specifications

UNSPSC

12352005

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/11-dehydro-thromboxane-b2-13c5.html

Solubility

10 mM in DMSO

Smiles

O=[13C]([13CH2][13CH2][13CH2]/[13CH]=C/C[C@H]([C@H](O1)/C=C/[C@H](CCCCC)O)[C@H](CC1=O)O)O

Molecular Formula

C15 13C5H32O6

Molecular Weight

373.43

References & Citations

[1]Simeone P, et al. Significance of urinary 11-dehydro-thromboxane B2 in age-related diseases: Focus on atherothrombosis. Ageing Res Rev. 2018 Dec;48:51-78. |[2]Lopez LR, et al. Platelet thromboxane (11-dehydro-Thromboxane B2) and aspirin response in patients with diabetes and coronary artery disease. World J Diabetes. 2014 Apr 15;5 (2) :115-27. |[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.