1H-Benzotriazol-1-yloxytris (dimethylamino) phosphonium Hexafluorophosphate

<strong> 1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate</strong>_x000D_ <strong>Catalog number:</strong> B2014885_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 g_x000D_ <strong>Molecular Weight or Concentration:</strong> 442.29_x000D_ <strong>Supplied as:</strong> Solid_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> RT_x000D_ <strong>Keywords:</strong> BOP, Castro's Reagent_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Singh MK, Lakshman MK. A simple synthesis of nitriles from aldoximes J Org Chem. 2009 Apr 17;74(8):3079-84._x000D_ 2: Nagy A, Szoke B, Schally AV. Selective coupling of methotrexate to peptide hormone carriers through a gamma-carboxamide linkage of its glutamic acid moiety: benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate activation in salt coupling Proc Natl Acad Sci U S A. 1993 Jul 1;90(13):6373-6._x000D_ 3: Akula HK, Kokatla H, Andrei G, Snoeck R, Schols D, Balzarini J, Yang L, Lakshman MK. Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products Org Biomol Chem. 2017 Feb 1;15(5):1130-1139._x000D_ 4: Akula HK, Lakshman MK. Facile Modifications at the C4 Position of Pyrimidine Nucleosides via In Situ Amide Activation with 1H-Benzotriazol-1-yloxy-tris(dimethyl-amino)phosphonium Hexafluorophosphate Curr Protoc Nucleic Acid Chem. 2019 Mar;76(1):e73._x000D_ 5: Brunel JM, Lieutaud A, Lome V, Pagès JM, Bolla JM. Polyamino geranic derivatives as new chemosensitizers to combat antibiotic resistant gram-negative bacteria Bioorg Med Chem. 2013 Mar 1;21(5):1174-9._x000D_ 6: Akula HK, Kokatla H, Andrei G, Snoeck R, Schols D, Balzarini J, Yang L, Lakshman MK. Correction: Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products Org Biomol Chem. 2017 Feb 1;15(5):1268._x000D_ 7: Wan ZK, Wacharasindhu S, Levins CG, Lin M, Tabei K, Mansour TS. The scope and mechanism of phosphonium-mediated S(N)Ar reactions in heterocyclic amides and ureas J Org Chem. 2007 Dec 21;72(26):10194-210._x000D_ 8: Steinauer R, Chen FM, Benoiton NL. Studies on racemization associated with the use of benzotriazol-1-yl-tris (dimethylamino)phosphonium hexafluorophosphate (BOP) Int J Pept Protein Res. 1989 Oct;34(4):295-8._x000D_ 9: Khandaker TA, Hess JD, Aguilera R, Andrei G, Snoeck R, Schols D, Pradhan P, Lakshman MK. Synthesis and Evaluations of "1,4-Triazolyl Combretacoumarins" and Desmethoxy Analogues European J Org Chem. 2019 Sep 8;2019(33):5610-5623._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/8391225">10: Fournier A, Couvineau A, Laburthe M. Synthesis of a hydrophilic affinity matrix for the purification of the vasoactive intestinal peptide receptor Anal Biochem. 1993 Jun;211(2):305-10. </a>_x000D_ _x000D_ <strong>Products Related to 1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>