20 (S) -Ginsenoside Rg3

20 (S) -Ginsenoside Rg3 is the main component of Panax ginseng C. A. Meyer. Ginsenoside Rg3 inhibits Na+ and hKv1.4 channel with IC50s of 32.2±4.5 and 32.6±2.2 μM, respectively. 20 (S) -Ginsenoside Rg3 also inhibits Aβ levels, NF-κB activity, and COX-2 expression.

Product Specifications

CAS Number

[14197-60-5]

Product Name Alternative

20 (S) -Propanaxadiol; S-ginsenoside Rg3

UNSPSC

12352005

Hazard Statement

H302

Target

Amyloid-β; COX; Endogenous Metabolite; NF-κB; Potassium Channel; Sodium Channel

Type

Natural Products

Related Pathways

Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Ginsenoside-Rg3.html

Purity

99.82

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@@H]([C@@H]([C@@H](CO)O1)O)[C@@H](O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)[C@@H]1O[C@H]3CC[C@]4(C)[C@@]5([H])C[C@@H](O)[C@]6([H])[C@@H](C(C)(O)CC/C=C(C)\C)CC[C@](C)6[C@@](C)5CCC4C3(C)C