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CDK9-IN-11

CDK9-IN-11 is a potent CDK9 inhibitor. CDK9-IN-11 is the ligand for the PROTAC CDK9 Degrader-1.

Product Specifications

CAS Number

2748368-15-0

UNSPSC

12352005

Target

CDK; Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; PROTAC

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cdk9-in-11.html

Purity

97.02

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NC1=NN(C(C2CCC2)=C1)C(OC(C)(C)C)=O)CC3=CC=C(C=C3)O

Molecular Formula

C20H25N3O4

Molecular Weight

371.43

References & Citations

[1]Robb CM, et al. Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC) . Chem Commun (Camb) . 2017 Jul 4;53 (54) :7577-7580.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CDK9

Available Sizes

Frequently Asked Questions

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