CDK9-IN-11
CDK9-IN-11 is a potent CDK9 inhibitor. CDK9-IN-11 is the ligand for the PROTAC CDK9 Degrader-1 (HY-103628) [1].
Product Specifications
CAS Number
[2748368-15-0]
UNSPSC
12352005
Target
CDK; Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk9-in-11.html
Purity
97.02
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=NN(C(C2CCC2)=C1)C(OC(C)(C)C)=O)CC3=CC=C(C=C3)O
Molecular Formula
C20H25N3O4
Molecular Weight
371.43
References & Citations
[1]Robb CM, et al. Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC) . Chem Commun (Camb) . 2017 Jul 4;53 (54) :7577-7580.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK9
Available Sizes
Curated Selection
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