L-Pyroglutamic Acid β-naphthylamide

<strong> L-Pyroglutamic Acid β-naphthylamide </strong>_x000D_ <strong>Catalog number:</strong> B2016100_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 g_x000D_ <strong>Molecular Weight or Concentration:</strong> 254.29 g/mol_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> L-Pyroglutamic acid β-naphthylamide_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Wilk S. Neuropeptide-specific peptidases: does brain contain a specific TRH-degrading enzyme? Life Sci. 1986 Oct 27;39(17):1487-92._x000D_ 2: Cummins PM, O'Connor B. Pyroglutamyl peptidase: an overview of the three known enzymatic forms Biochim Biophys Acta. 1998 Dec 8;1429(1):1-17._x000D_ 3: Segarra AB, Prieto I, Martinez-Canamero M, Vargas F, De Gasparo M, Vanderheyden P, Zorad S, Ramirez-Sanchez M. Cystinyl and pyroglutamyl-beta-naphthylamide hydrolyzing activities are modified coordinately between hypothalamus, liver and plasma depending on the thyroid status of adult male rats J Physiol Pharmacol. 2018 Apr;69(2)._x000D_ 4: Martínez JM, Ramírez MJ, Prieto I, Alba F, Ramírez M. Influence of dietary supplementation with olive oil on pyroglutamyl-beta-naphthylamide hydrolysing activity in serum and different tissues of mice Folia Biol (Praha). 1998;44(6):213-6._x000D_ 5: Chikuma T, Taguchi K, Yamaguchi M, Hojo H, Kato T. Improved determination of bovine glutaminyl cyclase activity using precolumn derivatization and reversed-phase high-performance liquid chromatography with ultraviolet detection J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Jul 5;806(2):113-8._x000D_ 6: Méndez M, Morán J, Wilk S, Joseph-Bravo P, Charli JL. Assessment of the role of TRH in the release of [3H]-dopamine from rat nucleus accumbens-lateral septum slices Brain Res Bull. 1993;31(5):621-5._x000D_ 7: Gallagher SP, O'Connor B. A study of a highly specific pyroglutamyl aminopeptidase type-II from the membrane fraction of bovine brain Int J Biochem Cell Biol. 1998 Jan;30(1):115-33._x000D_ 8: Bauer K. Purification and characterization of the thyrotropin-releasing-hormone-degrading ectoenzyme Eur J Biochem. 1994 Sep 1;224(2):387-96._x000D_ 9: Domínguez G, Ramírez M, Arechaga G. Day-night differences in membrane-bound pyroglutamyl-2-naphthylamide-hydrolyzing activity in rat hypothalamus, pituitary, and retina Chronobiol Int. 2006;23(4):767-77._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/6116600">10: Bauer K, Nowak P, Kleinkauf H. Specificity of a serum peptidase hydrolyzing thyroliberin at pyroglutamyl-histidine bone Eur J Biochem. 1981 Aug;118(1):173-6. </a>_x000D_ _x000D_ <strong>Products Related to L-Pyroglutamic Acid β-naphthylamide can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>