EJMC-1
EJMC-1 is a moderately potent TNF-α inhibitor with an IC50 value of 42 μM[1].
Product Specifications
CAS Number
[397281-20-8]
UNSPSC
12352005
Target
TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ejmc-1.html
Purity
99.39
Solubility
DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1NC2=CC=C(S(=O)(NC3=CC=C(C(Cl)=C3)O)=O)C4=C2C1=CC=C4
Molecular Formula
C17H11ClN2O4S
Molecular Weight
374.80
References & Citations
[1]Deng X, et al. Design, Synthesis, and Evaluation of Dihydrobenzo[cd]indole-6-sulfonamide as TNF-α Inhibitors. Front Chem. 2018 Apr 4;6:98.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TNFRSF5/CD40
Available Sizes
Curated Selection
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