ALK-7, Human (HEK293, Fc)

The recombinant human ALK-7 consists of 92 amino acids & hFc tag and predicts a molecular mass of 35.96 kDa. It migrates as an approximately 43-56 kDa band in SDS-PAGE under reducing conditions.

[1]M Rydén, et al. A novel type I receptor serine-threonine kinase predominantly expressed in the adult central nervous system. J Biol Chem. 1996 Nov 29;271 (48) :30603-9.|[2]Byung-Chul Kim, et al. Activin receptor-like kinase-7 induces apoptosis through activation of MAPKs in a Smad3-dependent mechanism in hepatoma cells. J Biol Chem. 2004 Jul 2;279 (27) :28458-65.|[3]Wen-bo Li, et al. Silencing of activin receptor-like kinase 7 alleviates aortic stiffness in type 2 diabetic rats. Acta Diabetol. 2015 Aug;52 (4) :717-26.|[4]Kunihiro Tsuchida, et al. Activin isoforms signal through type I receptor serine/threonine kinase ALK7. Mol Cell Endocrinol. 2004 May 31;220 (1-2) :59-65.