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Piperaquine-d6

Piperaquine-d6 is the deuterium labeled Piperaquine[1]. Piperaquine is a bisquinoline antimalarial agent. Piperaquine can be used in antimalarial research in combination with Artemisinin[2][3].

Product Specifications

CAS Number

1261394-71-1

UNSPSC

12352005

Target

Parasite

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Solubility

10 mM in DMSO

Smiles

ClC1=CC2=C(C=C1)C(N3CCN(CC3)C([2H])([2H])C([2H])([2H])C([2H])([2H])N4CCN(C5=CC=NC6=C5C=CC(Cl)=C6)CC4)=CC=N2

Molecular Formula

C29H26D6Cl2N6

Molecular Weight

541.55

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Moore BR, et, al. Pharmacokinetics and pharmacodynamics of piperaquine in a murine malaria model. Antimicrob Agents Chemother. 2008 Jan; 52 (1) : 306-11.|[3]Davis TME, et, al. Piperaquine: a resurgent antimalarial drug. Drugs. 2005; 65 (1) : 75-87.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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