Fenbendazole-d3
Fenbendazole-d3 is a deuterium labeled Fenbendazole. Fenbendazole-d3 is a HIF-1α agonist and activates the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53[1][2][3][4].
Product Specifications
CAS Number
1228182-47-5
UNSPSC
12352005
Hazard Statement
H361, H373, H410
Target
Antibiotic; HIF/HIF Prolyl-Hydroxylase; Microtubule/Tubulin; Parasite
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Cytoskeleton; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Infection
Purity
99.70
Solubility
DMSO : 5mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(OC([2H])([2H])[2H])NC1=NC2=CC=C(SC3=CC=CC=C3)C=C2N1
Molecular Formula
C15H10D3N3O2S
Molecular Weight
302.37
Precautions
H361, H373, H410
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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