Thyroxine sulfate
Thyroxine sulfate is a thyroid hormone metabolite.
Product Specifications
CAS Number
77074-49-8
Product Name Alternative
T4 Sulfate
UNSPSC
12352005
Target
Drug Metabolite; Endogenous Metabolite; Thyroid Hormone Receptor
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Thyroxine_sulfate.html
Purity
99.84
Solubility
DMSO : 140 mg/mL (ultrasonic)
Smiles
N[C@@H](CC1=CC(I)=C(C(I)=C1)OC2=CC(I)=C(OS(=O)(O)=O)C(I)=C2)C(O)=O
Molecular Formula
C15H11I4NO7S
Molecular Weight
856.93
References & Citations
[1]Wu SY, et al. Identification of thyroxine-sulfate (T4S) in human serum and amniotic fluid by a novel T4S radioimmunoassay. Thyroid. 1992 Summer;2 (2) :101-5.|[2]Rutgers M, et al. Effects of propylthiouracil on the biliary clearance of thyroxine (T4) in rats: decreased excretion of 3,5,3'-triiodothyronine glucuronide and increased excretion of 3,3',5'-triiodothyronine glucuronide and T4 sulfate. Endocrinology. 1989 Oct;125 (4) :2175-86.|[3]Peeters RP, et al. Increased thyroxine sulfate levels in critically ill patients as a result of a decreased hepatic type Ideiodinase activity. J Clin Endocrinol Metab. 2005 Dec;90 (12) :6460-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
Frequently Asked Questions
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