ACSS1, Human (P.pastoris, His)

ACSS1 Protein, Human (P.pastoris, His) is a mitochondrial matrix enzyme that is expressed in heart, skeletal muscle and brown adipose tissue. ACSS1 Protein, Human is involved in acetate-mediated epigenetic regulation.

ASGPSGSAPA VAAAAAQPGS YPALSAQAAR EPAAFWGPLA RDTLVWDTPY HTVWDCDFST GKIGWFLGGQ LNVSVNCLDQ HVRKSPESVA LIWERDEPGT EVRITYRELL ETTCRLANTL KRHGVHRGDR VAIYMPVSPL AVAAMLACAR IGAVHTVIFA GFSAESLAGR INDAKCKVVI TFNQGLRGGR VVELKKIVDE AVKHCPTVQH VLVAHRTDNK VHMGDLDVPL EQEMAKEDPV CAPESMGSED MLFMLYTSGS TGMPKGIVHT QAGYLLYAAL THKLVFDHQP GDIFGCVADI GWITGHSYVV YGPLCNGATS VLFESTPVYP NAGRYWETVE RLKINQFYGA PTAVRLLLKY GDAWVKKYDR SSLRTLGSVG EPINCEAWEW LHRVVGDSRC TLVDTWWQTE TGGICIAPRP SEEGAEILPA MAMRPFFGIV PVLMDEKGSV VEGSNVSGAL CISQAWPGMA RTIYGDHQRF VDAYFKAYPG YYFTGDGAYR TEGGYYQITG RMDDVINISG HRLGTAEIED AIADHPAVPE SAVIGYPHDI KGEAAFAFIV VKDSAGDSDV VVQELKSMVA TKIAKYAVPD EILVVKRLPK TRSGKVMRRL LRKIITSEAQ ELGDTTTLED PSIIAEILSV YQKCKDKQAA AK

[1]Moffett JR, et, al. Acetate Revisited: A Key Biomolecule at the Nexus of Metabolism, Epigenetics and Oncogenesis-Part 1: Acetyl-CoA, Acetogenesis and Acyl-CoA Short-Chain Synthetases. Front Physiol. 2020 Nov 12;11:580167.