Nebularine
Nebularine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[550-33-4]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Nucleoside Antimetabolite/Analog
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/nebularine.html
Purity
98.44
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC[C@@H](O1)[C@@H](O)[C@@H](O)[C@@H]1N2C=NC3=C2N=CN=C3
Molecular Formula
C10H12N4O4
Molecular Weight
252.23
Precautions
H315, H319
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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