BIZ 114
BIZ 114 (Example 11) is a fatty acid derivative and potent inhibits the TNF-α activated NF-κΒ pathway. BIZ 114 has the potential to prevent and / or treat ophthalmic disorders such as retinal degenerative disorders and ocular inflammatory diseases[1].
Product Specifications
CAS Number
[2099120-74-6]
UNSPSC
12352211
Target
NF-κB
Type
Reference compound
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/biz-114.html
Purity
98.0
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
CCC(OCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)C(O)=O
Molecular Formula
C24H40O3
Molecular Weight
376.57
References & Citations
[1]Anne Kristin Holmeide. pid compounds and compositions and their opthalmic use. WO2017093732A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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