(S) -Viloxazine (hydrochloride)

(S) -Viloxazine hydrochloride is the isomer of Viloxazine hydrochloride (HY-125784) . Viloxazine hydrochloride is the hydrochloride salt form of Viloxazine (HY-W380450) . Viloxazine (Viloxazin) hydrochloride is a norepinephrine reuptake inhibitor and a potent 5-HT2C agonist agent and 5-HT2B antagonist, EC50 for 5-HT2C b> is 32 μM, and the IC50 for 5-HT2B is 27 μM. Viloxazine hydrochloride's mechanism of action primarily involves serotonergic and noradrenergic pathways. Viloxazine hydrochloride is used in antidepressant research[1][2].

Product Specifications

CAS Number

[56287-61-7]

Product Name Alternative

(S) -Viloxazin (hydrochloride) ; (S) -Emovit (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302

Target

Adrenergic Receptor; Drug Isomer

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/s-viloxazine-hydrochloride.html

Smiles

CCOC1=CC=CC=C1OC[C@@H]2CNCCO2.Cl

Molecular Formula

C13H20ClNO3

Molecular Weight

273.76

Precautions

P264-P270-P330-P501

References & Citations

[1]Yu C, et al. New Insights into the Mechanism of Action of Viloxazine: Serotonin and Norepinephrine Modulating Properties. J Exp Pharmacol. 2020 Aug 25;12:285-300.|[2]Pinder RM, et al. Viloxazine: a review of its pharmacological properties and therapeutic efficacy in depressive illness. Drugs. 1977 Jun;13 (6) :401-21.