Sphondin
Sphondin possesses an inhibitory effect on IL-1β-induced increase in the level of COX-2 protein and PGE2 release in A549 cells[1].
Product Specifications
CAS Number
[483-66-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
COX
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sphondin.html
Purity
99.70
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C=CC2=C(C3=C(OC=C3)C(OC)=C2)O1
Molecular Formula
C12H8O4
Molecular Weight
216.19
Precautions
H302, H315, H319, H335
References & Citations
[1]Ling Ling Yang, et al. Effects of Sphondin, Isolated From Heracleum Laciniatum, on IL-1beta-induced cyclooxygenase-2 Expression in Human Pulmonary Epithelial Cells. Life Sci. 2002 Nov 29;72 (2) :199-213.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-2
Available Sizes
Curated Selection
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