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Sphondin

Sphondin possesses an inhibitory effect on IL-1β-induced increase in the level of COX-2 protein and PGE2 release in A549 cells[1].

Product Specifications

CAS Number

483-66-9

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

COX

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/sphondin.html

Purity

99.70

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C=CC2=C(C3=C(OC=C3)C(OC)=C2)O1

Molecular Formula

C12H8O4

Molecular Weight

216.19

Precautions

H302, H315, H319, H335

References & Citations

[1]Ling Ling Yang, et al. Effects of Sphondin, Isolated From Heracleum Laciniatum, on IL-1beta-induced cyclooxygenase-2 Expression in Human Pulmonary Epithelial Cells. Life Sci. 2002 Nov 29;72 (2) :199-213.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

COX-2

Available Sizes

Frequently Asked Questions

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