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Dimethylformamide- (S, R, S) -AHPC-CO-cyclohexane-pyrimidine-diazabicyclo

Dimethylformamide- (S, R, S) -AHPC-CO-cyclohexane-pyrimidine-diazabicyclo is an E3 Ligase Ligand-Linker Conjugate. Dimethylformamide- (S, R, S) -AHPC-CO-cyclohexane-pyrimidine-diazabicyclo can be used to synthesize PROTAC SMARCA2/4-degrader-2.

Product Specifications

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dimethylformamide-s-r-s-ahpc-co-cyclohexane-pyrimidine-diazabicyclo.html

Smiles

O=C(N1[C@@H](C[C@H](C1)O)C(NCC2=C(C=C(C3=C(N=CS3)C)C=C2)C(N(C)C)=O)=O)[C@H](C(C)(C)C)NC([C@H](CC4)CC[C@@H]4C5=CN=C(N=C5)N6C7CNCC6CC7)=O

Molecular Formula

C42H57N9O5S

Molecular Weight

800.02

References & Citations

[1]Preparation of heterocyclic compounds as SMARCA degraders and uses thereof. USA, US20230072658A1 2020-12-17

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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