Salvinorin A
Product Specifications
UNSPSC Description
Salvinorin A is a potent, unique and short-acting high efficacy kappa-opioid receptor (KOPr) agonist with Ki value of 4.3 nm. Salvinorin A is a non-nitrogenous neoclerodane isolated from Salvia divinorum.
Target Antigen
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/salvinorin-a.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@]3([H])[C@]([C@@H](C[C@@H](C3=O)OC(C)=O)C(OC)=O)(CC[C@@]1([H])C(O[C@H](C4=COC=C4)C2)=O)C
Molecular Weight
432.46
References & Citations
[1]Butelman ER, et al. Salvinorin A, a kappa-opioid receptor agonist hallucinogen: pharmacology and potential template for novel pharmacotherapeutic agents in neuropsychiatric disorders. Front Pharmacol. 2015 Sep 8;6:190.|[2]John TF, et al. The antinociceptive effect of salvinorin A in mice.Eur J Pharmacol. 2006 Sep 18;545(2-3):129-33. Epub 2006 Jul 4.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-100845/Salvinorin-A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-100845/Salvinorin-A-SDS-MedChemExpress.pdf
Clinical Information
Phase 1
CAS Number
83729-01-5
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