AIP-II
AIP-II is a macrocyclic peptide signaling molecule used for quorum sensing, which can be produced be Staphylococcus aureus. AIP-II binds to AgrC-II receptor, regulates the virulence gene expression in Staphylococcus aureus. AIP-II is an antagonist for AgrC-I receptor[1].
Product Specifications
CAS Number
200010-31-7
UNSPSC
12352209
Target
Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/aip-ii.html
Purity
98.04
Smiles
O=C([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CSC1=O)NC([C@H](C)NC([C@H](CC(N)=O)NC([C@H](C(C)C)NC(CN)=O)=O)=O)=O)=O)CO)=O)CO)=O)CC(C)C)N[C@H]1CC2=CC=CC=C2
Molecular Formula
C38H58N10O12S
Molecular Weight
878.99
References & Citations
[1]Tal-Gan Y, et al., Structural characterization of native autoinducing peptides and abiotic analogues reveals key features essential for activation and inhibition of an AgrC quorum sensing receptor in Staphylococcus aureus. J Am Chem Soc. 2013 Dec 11;135 (49) :18436-44.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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