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NH2-PEG7

NH2-PEG7 is a PROTAC linker, which refers to the PEG composition. NH2-PEG7 can be used in the synthesis of the PROTAC PARP1 degrader iRucaparib-AP6[1].

Product Specifications

CAS Number

1425973-14-3

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nh2-peg7.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OCCOCCOCCOCCOCCOCCOCCN

Molecular Formula

C14H31NO7

Molecular Weight

325.40

Precautions

H315, H319, H335

References & Citations

[1]Wang S, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation. Nat Chem Biol. 2019 Dec;15 (12) :1223-1231.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Frequently Asked Questions

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